Nuclear receptor ROR-beta (RORb) Antibody (Biotin)
260€ (50 µl)
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Name
Nuclear receptor ROR-beta (RORb) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx340875
Tested Applications
ELISA
Description
Nuclear receptor ROR-beta (RORb) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human RORB.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nuclear receptor ROR-beta (RORb) Immunogen: Recombinant Human Nuclear receptor ROR-beta protein (1-269 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by antigen affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q92753 |
| OMIM | 601972 |
| Alias | RZRB,EIG15,NR1F2,RORbeta,ROR-BETA,RZR-BETA,Nuclear receptor ROR-beta,Nuclear receptor RZR-beta,Nuclear receptor subfamily 1 group F member 2 |
| Background | Antibody anti-RORB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAR related orphan receptor B (RORB) is another member of the ROR family of nuclear receptors, playing a critical role in regulating the development of the central nervous system and circadian rhythms RORB is particularly important for the development of the retina and the regulation of visual processing, where it modulates the expression of genes involved in retinal cell differentiation and function It also participates in regulating the transcription of genes related to metabolism and cell growth, affecting cellular differentiation in multiple tissues RORB is involved in the regulation of sleep-wake cycles by modulating the circadian clock and influencing the expression of key clock genes Disruption in RORB expression is linked to several neurological disorders, including sleep disturbances and retinal degeneration, and may contribute to diseases like bipolar disorder and schizophrenia Its role in neurodevelopment and circadian regulation makes RORB a target for therapies aimed at treating neurological diseases and circadian rhythm disorders
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