Nuclear Factor, Erythroid 2 (NFE2) Antibody

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Description
NFE2 Antibody is a Rabbit Polyclonal against NFE2.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Nuclear Factor, Erythroid 2 (NFE2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | ≥ 95% (SDS-PAGE) |
Purification | Purified by immunogen affinity chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q16621 |
Gene ID | 4778 |
OMIM | 601490 |
Background | Antibody anti-NFE2 |
Status | RUO |
Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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NFE2 antibody
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2(HS2) of the beta-globin control region(LCR). This subunit(NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
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Nuclear Factor, Erythroid 2 (NFE2) Antibody
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
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Nuclear Factor, Erythroid 2 (NFE2) Antibody
NFE2 Antibody is a Rabbit Polyclonal against NFE2.
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