NTRK1 (pY791) Antibody
429€ (100 µl)
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Name
NTRK1 (pY791) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx332861
Tested Applications
ELISA, IHC
Description
NTRK1 (pY791) Antibody is a Rabbit Polyclonal against NTRK1 (pY791).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: NTRK1 (pY791) Immunogen: Peptide sequence around phosphorylation site of tyrosine 791 (P-V-Y (p)-L-D) derived from Human Trk A. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS (without Mg2+ and Ca2+), pH 7.4, containing 150mM NaCl, 0.02% sodium azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04629 |
| Alias | MTC,TRK,TRK1,TRKA,rk-A,p140-TrkA,Tyrosine kinase receptor A,TRK1-transforming tyrosine kinase protein,Neurotrophic tyrosine kinase receptor type 1,High affinity nerve growth factor receptor |
| Background | Antibody anti-NTRK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Neurotrophic receptor tyrosine kinase 1 (NTRK1) is an essential receptor that binds with nerve growth factor (NGF), initiating critical signaling cascades required for the survival, differentiation, and functional maintenance of neurons, particularly within the peripheral nervous system. Beyond supporting neuronal growth, NTRK1 contributes to injury responses, helping facilitate neuronal repair and regeneration. Dysregulation or mutations in NTRK1 have been implicated in neurodegenerative diseases, such as Charcot-Marie-Tooth disease, as well as in certain cancers, making it a significant target for therapeutic research and drug development efforts.
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