NmrA-Like Family Domain-Containing Protein 1 (NMRAL1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
NMRAL1 Antibody is a Rabbit Polyclonal against NMRAL1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NmrA-Like Family Domain-Containing Protein 1 (NMRAL1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HBL8 |
| Gene ID | 57407 |
| Background | Antibody anti-NMRAL1 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Related Products
NMRAL1 antibody
Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase(ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.
Ver Producto
Recombinant Human NMRAL1
Ver Producto
NmrA-Like Family Domain-Containing Protein 1 (NMRAL1) Antibody
NMRAL1 Antibody is a Rabbit Polyclonal against NMRAL1.
Ver Producto