NFKB1 (pS337) Antibody
208€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
NFKB1 (pS337) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000177
Tested Applications
ELISA, WB
Description
NFKB1 (pS337) Antibody is a Rabbit Polyclonal antibody against NFKB1 (pS337). This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: NFKB1 (pS337) Immunogen: Synthetic peptide corresponding to NFKB1 (pS337). The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 105 kDa Observed MW: 120 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P19838 |
| Gene ID | 4790 |
| NCBI Accession | NP_001158884.1 |
| Background | Antibody anti-NFKB1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
NFKB1 (pS337) Antibody
NFKB1 (pS337) Antibody is a Rabbit Polyclonal antibody against NFKB1 (pS337). This gene encodes a 105 kD protein which c…
Ver producto
NFKB1 (pS927) Antibody
NFKB1 (pS927) Antibody is a Rabbit Polyclonal antibody against NFKB1 (pS927). This gene encodes a 105 kD protein which c…
Ver producto
NFKB1 (pS893) Antibody
NFKB1 (pS893) Antibody is a Rabbit Polyclonal antibody against NFKB1 (pS893). This gene encodes a 105 kD protein which c…
Ver producto