NFKB Repressing Factor (NKRF) Antibody
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Description
NFKB Repressing Factor (NKRF) Antibody is a Rabbit Polyclonal antibody against NFKB Repressing Factor (NKRF).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NFKB Repressing Factor (NKRF) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O15226 |
| Gene ID | 55922 |
| Background | Antibody anti-NKRF |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Interacts with a specific negative regulatory element(NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
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NFKB Repressing Factor (NKRF) Antibody
NKRF Antibody is a Rabbit Polyclonal antibody against NKRF. This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants.
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