NKRF antibody
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Description
Interacts with a specific negative regulatory element(NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NFKB repressing factor (NKRF) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 100 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O15226 |
| Gene ID | 55922 |
| Alias | NF-kappa-B-repressing factor (NFkB-repressing factor, NRF),Protein ITBA4,NKRF,ITBA4,NRF |
| Background | Antibody anti-NKRF |
| Status | RUO |
| Note | Mol. Weight 100 kDa |
Descripción
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