Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody
819€ (1 ml)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx173814
Tested Applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Neutral Sphingomyelinase Activation Associated Factor (NSMAF) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | FAN,GRAMD5,Protein FAN |
| Background | Antibody anti-NSMAF |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Neutral sphingomyelinase activation associated factor (NSMAF) is a key protein involved in the regulation of sphingomyelin metabolism, specifically in the activation of neutral sphingomyelinase (nSMase). This enzyme plays an important role in generating ceramide, a lipid molecule involved in various cellular processes, including apoptosis, cell differentiation, and membrane integrity. NSMAF functions as an activator of nSMase, and its activity is crucial for the proper regulation of sphingomyelinase signaling pathways. The activation of nSMase by NSMAF is essential for maintaining cellular homeostasis and regulating lipid metabolism, especially in response to external stimuli such as oxidative stress or inflammatory signals. Disruption of NSMAF function can lead to abnormal ceramide production, which has been linked to several diseases, including neurodegenerative conditions, cancers, and metabolic disorders. Understanding the role of NSMAF in sphingomyelinase regulation is important for developing potential therapeutic strategies targeting ceramide-related pathways in various diseases.
Productos relacionados
Protein FAN (NSMAF) Antibody
Protein FAN (NSMAF) antibody is a Rabbit polyclonal against Protein FAN (NSMAF).…
Ver producto
Neutral Sphingomyelinase Activation Associated Factor (NSMAF) Antibody
Neutral Sphingomyelinase Activation Associated Factor Antibody is a Rabbit Polyclonal against Neutral Sphingomyelinase A…
Ver producto
Human Neutral Sphingomyelinase Activation Associated Factor (NSMAF) ELISA Kit
Human Neutral Sphingomyelinase Activation Associated Factor (NSMAF) ELISA Kit is an ELISA Kit for the in vitro quantitat…
Ver producto