Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) Antibody
286€ (100 µl)
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Name
Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx128065
Tested Applications
WB
Description
Neurotrophic Tyrosine Kinase Receptor Type 2 Antibody is a Rabbit Polyclonal against Neurotrophic Tyrosine Kinase Receptor Type 2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) Immunogen: NTRK2 (Cys32-His430) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1-5 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q16620 |
| Alias | OBHD,TRKB,DEE58,trk-B,EIEE58,GP145-TrkB,Tropomyosin-related kinase B,TrkB tyrosine kinase,Neurotrophic tyrosine kinase receptor type 2,BDNF/NT-3 growth factors receptor |
| Background | Antibody anti-NTRK2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Neurotrophic receptor tyrosine kinase 2 (NTRK2), often referred to as TrkB, interacts specifically with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5). This receptor is central to processes like neuroplasticity, synaptic strength regulation, and long-term potentiation—mechanisms foundational for cognitive functions such as learning and memory. In addition to its role in brain health, NTRK2 is involved in mood regulation, and aberrations in its signaling pathways are associated with neuropsychiatric disorders, including depression, anxiety, and schizophrenia, emphasizing its role in mental health research and therapeutic interventions.
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