Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) Antibody

Este producto es parte de NTRK - neurotrophic receptor tyrosine kinase
Product Graph
286€ (100 µl)

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935106861
info@markelab.com
name
Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx128065
tested applications
WB, IHC, IF/ICC

Description

Neurotrophic Tyrosine Kinase Receptor Type 2 Antibody is a Rabbit Polyclonal against Neurotrophic Tyrosine Kinase Receptor Type 2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1-5 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q16620
Alias
OBHD,TRKB,DEE58,trk-B,EIEE58,GP145-TrkB,Tropomyosin-related kinase B,TrkB tyrosine kinase,Neurotrophic tyrosine kinase receptor type 2,BDNF/NT-3 growth factors receptor
Background
Antibody anti-NTRK2
Status
RUO

Descripción

Neurotrophic receptor tyrosine kinase 2 (NTRK2), often referred to as TrkB, interacts specifically with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5). This receptor is central to processes like neuroplasticity, synaptic strength regulation, and long-term potentiation—mechanisms foundational for cognitive functions such as learning and memory. In addition to its role in brain health, NTRK2 is involved in mood regulation, and aberrations in its signaling pathways are associated with neuropsychiatric disorders, including depression, anxiety, and schizophrenia, emphasizing its role in mental health research and therapeutic interventions.

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