Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2) Antibody
Pida mas información
935106861
info@markelab.com
Precio
175€ (20 µl)
Antibody anti-NTRK2
proveedor
Abbexareference
abx001711Tested Applications
WB, IF/ICCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
NTRK2 Antibody is a Rabbit Polyclonal antibody against NTRK2. This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Background
Neurotrophic receptor tyrosine kinase 2 (NTRK2), often referred to as TrkB, interacts specifically with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5). This receptor is central to processes like neuroplasticity, synaptic strength regulation, and long-term potentiation—mechanisms foundational for cognitive functions such as learning and memory. In addition to its role in brain health, NTRK2 is involved in mood regulation, and aberrations in its signaling pathways are associated with neuropsychiatric disorders, including depression, anxiety, and schizophrenia, emphasizing its role in mental health research and therapeutic interventions.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Neurotrophic Tyrosine Kinase Receptor Type 2 (NTRK2)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB, IF/ICC
purification
Purified by affinity chromatography.
buffer
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
size 1
20 µl
size 2
50 µl
size 3
100 µl
size 4
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
NTRK2
dry ice
No
availability
Shipped within 5-10 working days.
alias
OBHD,TRKB,DEE58,trk-B,EIEE58,GP145-TrkB,Tropomyosin-related kinase B,TrkB tyrosine kinase,Neurotrophic tyrosine kinase receptor type 2,BDNF/NT-3 growth factors receptor
uniprot id
NCBI accession
NP_001018074.1
note
This product is for research use only.
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