Neurotrophic Receptor Tyrosine Kinase 2 Phospho-Tyr706/Y707 (NTRK2 pY706/Y707) Antibody

Este producto es parte de NTRK - neurotrophic receptor tyrosine kinase
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221€ (50 µg)

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935106861
info@markelab.com
name
Neurotrophic Receptor Tyrosine Kinase 2 Phospho-Tyr706/Y707 (NTRK2 pY706/Y707) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx326432
tested applications
ELISA, IHC

Description

NTRK2 (pY706/Y707) Antibody is a Rabbit Polyclonal against NTRK2 (pY706/Y707).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetNeurotrophic Receptor Tyrosine Kinase 2 Phospho-Tyr706/Y707 (NTRK2 pY706/Y707)
HostRabbit
ReactivityHuman, Mouse, Rat
Assay DataModification: Phosphorylation // Target Modification: Tyr706/707
Recommended DilutionELISA: 1/10000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by affinity chromatography.
Size 150 µg
Size 2100 µg
FormLiquid
Tested ApplicationsELISA, IHC
BufferPBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ16620
Gene ID4915
AliasOBHD,TRKB,DEE58,trk-B,EIEE58,GP145-TrkB,Tropomyosin-related kinase B,TrkB tyrosine kinase,Neurotrophic tyrosine kinase receptor type 2,BDNF/NT-3 growth factors receptor
BackgroundAntibody anti-NTRK2
StatusRUO
NoteConcentration: 1 mg/ml -

Descripción

Neurotrophic receptor tyrosine kinase 2 (NTRK2), often referred to as TrkB, interacts specifically with brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5). This receptor is central to processes like neuroplasticity, synaptic strength regulation, and long-term potentiation—mechanisms foundational for cognitive functions such as learning and memory. In addition to its role in brain health, NTRK2 is involved in mood regulation, and aberrations in its signaling pathways are associated with neuropsychiatric disorders, including depression, anxiety, and schizophrenia, emphasizing its role in mental health research and therapeutic interventions.

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