Neurotrophic Receptor Tyrosine Kinase 1 Phospho-Tyr791 (NTRK1 pY791) Antibody
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Description
NTRK1 (pY791) Antibody is a Rabbit Polyclonal against NTRK1 (pY791).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neurotrophic Receptor Tyrosine Kinase 1 Phospho-Tyr791 (NTRK1 pY791) |
| Host | Rabbit |
| Reactivity | Human |
| Assay Data | Modification: Phosphorylation // Target Modification: Tyr791 |
| Recommended Dilution | ELISA: 1/5000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04629 |
| Gene ID | 4914 |
| Alias | MTC,TRK,TRK1,TRKA,rk-A,p140-TrkA,Tyrosine kinase receptor A,TRK1-transforming tyrosine kinase protein,Neurotrophic tyrosine kinase receptor type 1,High affinity nerve growth factor receptor |
| Background | Antibody anti-NTRK1 |
| Status | RUO |
Descripción
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NTRK1 (pS791) Antibody is a Rabbit Polyclonal antibody against NTRK1 (pS791). This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
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