Neuromedin U Receptor 2 (NMUR2) Antibody
221€ (50 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Neuromedin U Receptor 2 (NMUR2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx324995
tested applications
ELISA, WB
Description
NMUR2 Antibody is a Rabbit Polyclonal against NMUR2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neuromedin U Receptor 2 (NMUR2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000 - 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9GZQ4 |
| Gene ID | 56923 |
| Alias | NMUR2,FM-4,FM4,NMU-R,TGR-1,TGR1,SNORF72 |
| Background | Antibody anti-NMUR2 |
| Status | RUO |
Descripción
NMUR2 is a G protein-coupled receptor activated by neuromedin U (NMU) and is predominantly expressed in the central nervous system (CNS), particularly in the hypothalamus, brainstem, and spinal cord. NMUR2 couples to Gq/11 proteins, activating downstream pathways such as phospholipase C (PLC) and calcium signaling. NMUR2 plays a critical role in regulating energy balance, feeding behavior, and stress responses. In the hypothalamus, NMUR2 activation suppresses appetite and enhances energy expenditure, linking it to the regulation of obesity and metabolic homeostasis. NMUR2 is also involved in the modulation of pain perception and stress-induced behaviors, with emerging evidence suggesting its role in anxiety and inflammatory pain pathways. Dysregulation of NMUR2 has been associated with metabolic disorders, stress-related diseases, and chronic pain conditions. NMUR2 agonists are being explored as potential therapeutic agents for obesity and metabolic syndrome, while antagonists may be beneficial for pain and stress-related disorders, highlighting its dual role in energy regulation and pain modulation.
Related Products
Neuromedin U Receptor 2 (NMUR2) Antibody
NMUR2 Antibody is a Rabbit Polyclonal against NMUR2.
Ver Producto
Human Neuromedin-U receptor 2 (NMUR2) ELISA Kit
Human Neuromedin-U receptor 2 (NMUR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neuromedin-U receptor 2 (NMUR2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver ProductoMouse Neuromedin-U receptor 2 (NMUR2) ELISA Kit
Mouse Neuromedin-U receptor 2 (NMUR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Neuromedin-U receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto