Neurobeachin (NBEA) Antibody
260€ (50 µl)
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935106861
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name
Neurobeachin (NBEA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx212193
tested applications
ELISA, IHC
Description
NBEA Antibody is a Rabbit Polyclonal against NBEA.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neurobeachin (NBEA) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/1000 - 1/5000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFP9 |
| Gene ID | 26960 |
| Alias | BCL8B,LYST2,NEDEGE,Protein BCL8B,Lysosomal-trafficking regulator 2 |
| Background | Antibody anti-NBEA |
| Status | RUO |
Descripción
Neurobeachin (NBEA) is a multi-domain protein involved in the regulation of synaptic function, neuronal signaling, and cell adhesion NBEA is particularly abundant in the brain, where it plays a role in neuronal growth, synaptic plasticity, and the maintenance of neuronal structure It interacts with a variety of proteins involved in synaptic signaling and vesicle trafficking, contributing to the organization of the postsynaptic density and the regulation of neurotransmitter receptor trafficking NBEA is essential for the proper function of neurons, particularly in areas involved in learning and memory, and its dysfunction is linked to neurological disorders such as neurodevelopmental disorders and intellectual disability Mutations in NBEA disrupt neuronal connectivity and signaling, leading to impaired cognitive function Understanding NBEA’s role in neuronal health could provide insights into therapies for treating neurodevelopmental and neurodegenerative diseases
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