Neurobeachin-Like Protein 2 (NBEAL2) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Neurobeachin-Like Protein 2 (NBEAL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx313495
tested applications
ELISA, IHC, IF/ICC
Description
NBEAL2 Antibody is a Rabbit Polyclonal against NBEAL2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neurobeachin-Like Protein 2 (NBEAL2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6ZNJ1 |
| Gene ID | 23218 |
| NCBI Accession | NP_055990.1, NM_015175.2 |
| OMIM | 139090 |
| Alias | ALS2CR16,ALS2CR17,Neurobeachin-like protein 1,Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein,Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein |
| Background | Antibody anti-NBEAL2 |
| Status | RUO |
| Note | Concentration: 3 mg/ml - |
Descripción
Neurobeachin like 2 (NBEAL2), another member of the neurobeachin family, shares many functional similarities with NBEAL1 and is involved in regulating the actin cytoskeleton and intracellular signaling NBEAL2 plays an important role in the development and function of neurons and has been shown to contribute to synaptic function, cellular signaling, and vesicular trafficking within the nervous system Its activity is important for maintaining proper neuronal communication and supporting processes such as synaptic plasticity, which is essential for learning and memory Additionally, NBEAL2 has been implicated in the formation and maintenance of specialized cellular structures like dendritic spines, which are involved in synaptic signaling Dysregulation of NBEAL2 has been linked to neurodevelopmental disorders, where impaired function leads to cognitive deficits and abnormal neuronal connectivity Understanding NBEAL2’s precise mechanisms in neurodevelopment and signaling may provide insights into new therapeutic approaches for neurodevelopmental diseases and synaptic disorders
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