Neuregulin 2 (NRG2) Antibody (HRP)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
NRG2 Antibody (HRP) is a Rabbit Polyclonal against NRG2 conjugated to HRP.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neuregulin 2 (NRG2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O14511 |
| Gene ID | 9542 |
| NCBI Accession | NP_001171864.1, NM_001184935.1, NP_004874.1, NM_004883.2 |
| OMIM | 603818 |
| Alias | DON1,HRG2,NTAK,Pro-NRG2,Pro-neuregulin-2 membrane-bound isoform,Divergent of neuregulin-1,Neural- and thymus-derived activator for ERBB kinases |
| Background | Antibody anti-NRG2 |
| Status | RUO |
Descripción
Neuregulin 2 (NRG2), though structurally similar to NRG1, displays distinct expression patterns and specialized functions. Predominantly found in the brain, NRG2 is integral to synaptic stability, neurotransmission, and neural development. By signaling through ErbB receptor pathways, NRG2 contributes to the interactions between neurons and glial cells, thus supporting neural network formation and maintenance. Research has begun to associate NRG2 with neuropsychiatric disorders, cognitive processes, and neuroplasticity. These emerging links make it a promising area for exploration in understanding the mechanisms underlying mental health conditions and potential therapeutic interventions.
Related Products
Human NRG-2(Neuregulin 2) ELISA Kit
Ver Producto
Rat NRG-2(Neuregulin 2) ELISA Kit
Ver Producto
Neuregulin 2 (NRG2) Antibody
Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.
Ver Producto