Human Neuregulin 2 (NRG2) Protein
234€ (10 µg)
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Name
Human Neuregulin 2 (NRG2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx068239
Tested Applications
WB, SDS-PAGE
Description
Human Neuregulin 2 (NRG2) is a recombinant Human protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Neuregulin 2 (NRG2) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Phe101-Phe211 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 13.3 kDa Observed MW (SDS-PAGE): 14 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | O14511 |
| Gene ID | 9542 |
| OMIM | 603818 |
| Alias | DON1,HRG2,NTAK,Pro-NRG2,Pro-neuregulin-2 membrane-bound isoform,Divergent of neuregulin-1,Neural- and thymus-derived activator for ERBB kinases |
| Background | Protein NRG2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
Neuregulin 2 (NRG2), though structurally similar to NRG1, displays distinct expression patterns and specialized functions. Predominantly found in the brain, NRG2 is integral to synaptic stability, neurotransmission, and neural development. By signaling through ErbB receptor pathways, NRG2 contributes to the interactions between neurons and glial cells, thus supporting neural network formation and maintenance. Research has begun to associate NRG2 with neuropsychiatric disorders, cognitive processes, and neuroplasticity. These emerging links make it a promising area for exploration in understanding the mechanisms underlying mental health conditions and potential therapeutic interventions.
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