Netrin Receptor UNC5B (Unc5b) Antibody

Este producto es parte de UNC5 - unc-5 netrin receptor
Netrin Receptor UNC5B (Unc5b) Antibody

Pida mas información

935106861

info@markelab.com

Precio

250€ (200 µl)

Antibody anti-UNC5B

proveedor

Abbexa

reference

abx431031

Tested Applications

P-ELISA

reactivity

Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

Unc5b Antibody is a Goat Polyclonal antibody against Unc5b.


Background

unc-5 netrin receptor B (UNC5B) acts as a receptor for netrin-1, orchestrating key cellular processes like axonal guidance and vascular development. UNC5B ensures proper vascular and neuronal organization by transmitting repellent cues that direct cellular movements. In endothelial cells, UNC5B is vital for angiogenesis, controlling endothelial migration and sprouting. Beyond developmental contexts, UNC5B is implicated in tumor suppression through apoptosis activation in netrin-1’s absence, akin to its role as a dependence receptor. Dysregulation of UNC5B has been linked to pathological angiogenesis and malignancies, highlighting its dual importance in both developmental and pathological processes.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Mouse, Rat


immunogen target

Netrin Receptor UNC5B (Unc5b)


host

Goat


conjugation

Unconjugated


form

Liquid


tested applications

P-ELISA


purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.


buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.


size 1

200 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

UNC5B


dry ice

No


availability

Shipped within 1-3 working days.


alias

UNC5H2,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,p53-regulated receptor for death and life protein 1,Netrin receptor UNC5B


NCBI accession

NP_084046.2


note

This product is for research use only.


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reactivity

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status

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