Name: Netrin Receptor UNC5B (UNC5B) Antibody
Brand: Abbexa
SKU: abx431030
Price: 387.5 EUR
Availability: OnlineOnly

Background

unc-5 netrin receptor B (UNC5B) acts as a receptor for netrin-1, orchestrating key cellular processes like axonal guidance and vascular development. UNC5B ensures proper vascular and neuronal organization by transmitting repellent cues that direct cellular movements. In endothelial cells, UNC5B is vital for angiogenesis, controlling endothelial migration and sprouting. Beyond developmental contexts, UNC5B is implicated in tumor suppression through apoptosis activation in netrin-1’s absence, akin to its role as a dependence receptor. Dysregulation of UNC5B has been linked to pathological angiogenesis and malignancies, highlighting its dual importance in both developmental and pathological processes.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Netrin Receptor UNC5B (UNC5B)

host

Goat

conjugation

Unconjugated

form

Liquid

tested applications

P-ELISA, WB

purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

size 1

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

UNC5B

dry ice

availability

Shipped within 1-3 working days.

alias

UNC5H2,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,p53-regulated receptor for death and life protein 1,Netrin receptor UNC5B

gene id

https://www.ncbi.nlm.nih.gov/gene/219699 https://www.ncbi.nlm.nih.gov/gene/107449 https://www.ncbi.nlm.nih.gov/gene/60630

NCBI accession

NP_734465.2

note

This product is for research use only.

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Human UNC5B(Netrin Receptor UNC5B) ELISA Kit

proveedor

FineTest

reference

EH4330

reactivity

human

status

RUO

Precio a consultar

Human Netrin receptor UNC5B (UNC5B) ELISA Kit

proveedor

Abbexa

reference

abx259097

Tested Applications

ELISA

reactivity

Human

status

RUO

Human Netrin receptor UNC5B (UNC5B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Netrin ...

687.5€ (96 tests)