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Netrin Receptor DCC (DCC) Antibody
Pida mas información
935106861
info@markelab.com
Precio
250€ (80 µl)
Antibody anti-DCC
proveedor
Abbexareference
abx026737Tested Applications
ELISA, WB, IHCreactivity
Mousestatus
RUOclonality
PolyclonalDescripción
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Mouse
immunogen target
Netrin Receptor DCC (DCC)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purification
Purified through a protein A column, followed by peptide affinity purification.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
DCC
dry ice
No
availability
Shipped within 5-10 working days.
alias
CRC18,CRCR1,MRMV1,HGPPS2,IGDCC1,NTN1R1,Tumor suppressor protein DCC,Immunoglobulin superfamily DCC subclass member 1,Colorectal cancer suppressor
uniprot id
note
This product is for research use only.
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