Nectin-4 (NECTIN4) Antibody (FITC)
169€ (20 µg)
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Name
Nectin-4 (NECTIN4) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx340915
Description
Nectin-4 (NECTIN4) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human NECTIN4.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nectin-4 (NECTIN4) Immunogen: Recombinant Human Nectin-4 protein (91-199 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96NY8 |
| Gene ID | 8167 |
| Alias | LNIR,PRR4,EDSS1,PVRL4,nectin-4,Ig superfamily receptor LNIR,Nectin cell adhesion molecule 4,Poliovirus receptor-related protein 4 |
| Background | Antibody anti-NECTIN4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nectin cell adhesion molecule 4 (NECTIN4) is highly expressed in epithelial tissues and has emerged as a significant player in cancer biology. Its overexpression is linked to the progression of aggressive cancers, including breast and urothelial carcinomas. NECTIN4 promotes tumor growth and metastasis by activating key signaling pathways such as PI3K/AKT and MAPK, which drive cell proliferation, survival, and migration. Its expression has also been associated with poor clinical outcomes, making it a potential biomarker and therapeutic target for cancer treatment strategies.
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