Nectin Cell Adhesion Molecule 4 (NECTIN4) Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
Nectin Cell Adhesion Molecule 4 (NECTIN4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx213127
tested applications
ELISA, WB, IHC
Description
PVRL4 Antibody is a Rabbit Polyclonal against PVRL4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nectin Cell Adhesion Molecule 4 (NECTIN4) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96NY8 |
| Gene ID | 81607 |
| Alias | LNIR,PRR4,EDSS1,PVRL4,nectin-4,Ig superfamily receptor LNIR,Nectin cell adhesion molecule 4,Poliovirus receptor-related protein 4 |
| Background | Antibody anti-NECTIN4 |
| Status | RUO |
Descripción
Nectin cell adhesion molecule 4 (NECTIN4) is highly expressed in epithelial tissues and has emerged as a significant player in cancer biology. Its overexpression is linked to the progression of aggressive cancers, including breast and urothelial carcinomas. NECTIN4 promotes tumor growth and metastasis by activating key signaling pathways such as PI3K/AKT and MAPK, which drive cell proliferation, survival, and migration. Its expression has also been associated with poor clinical outcomes, making it a potential biomarker and therapeutic target for cancer treatment strategies.
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