Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
312€ (50 µg)
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935106861
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name
Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421332
tested applications
FCM
Description
Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody is a Mouse Monoclonal antibody for the detection of Natural Cytotoxicity Triggering Receptor 1 (NCR1) in Human samples.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Natural Cytotoxicity Triggering Receptor 1 (NCR1) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | P930 |
| Purity | > 95% |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | O76036 |
| Gene ID | 9437 |
| NCBI Accession | NP_001138929.2 |
| Alias | Lymphocyte antigen 94 homolog,LY94,CD335,NKP46,NK-p46,NK cell-activating receptor,Natural killer cell p46-related protein |
| Background | Antibody anti-NCR1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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NCR1 antibody
The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.
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