NADH:Ubiquinone Oxidoreductase Core Subunit S8 (NDUFS8) Antibody

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292.5€ (80 µl)

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935106861
info@markelab.com
name
NADH:Ubiquinone Oxidoreductase Core Subunit S8 (NDUFS8) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx026882
tested applications
ELISA, WB, IHC

Description

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
NADH:Ubiquinone Oxidoreductase Core Subunit S8 (NDUFS8)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O00217
Gene ID
4728
OMIM
602141
Background
Antibody anti-NDUFS8
Status
RUO
Note
Concentration: 0.48 mg/ml -

Descripción

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NADH:Ubiquinone Oxidoreductase Core Subunit S8 (NDUFS8) Antibody

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

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