NACHT, LRR And PYD Domains-Containing Protein 3 (NLRP3) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
NACHT, LRR And PYD Domains-Containing Protein 3 (NLRP3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx034000
Tested Applications
ELISA, WB, IHC
Description
NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: NACHT, LRR And PYD Domains-Containing Protein 3 (NLRP3) Immunogen: KLH-conjugated synthetic peptide between 65-91 amino acids from the N-terminal region of human NLRP3. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000 - 1/2000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 118 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96P20 |
| NCBI Accession | NP_001073289.1, NP_001120933.1, NP_001120934.1, NP_001230062.1, NP_004886.3, NP_899632.1 |
| Background | Antibody anti-NLRP3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
NACHT, LRR And PYD Domains-Containing Protein 3 (NLRP3) Antibody
NLRP3 Antibody is a Rabbit Polyclonal antibody against NLRP3. This gene encodes a pyrin-like protein containing a pyrin …
Ver producto NACHT, LRR And PYD Domains-Containing Protein 3 (NLRP3) Antibody
NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repe…
Ver producto
NACHT, LRR And PYD Domains-Containing Protein 3 (NLRP3) Antibody
Rabbit Polyclonal against the NLRP3 protein.…
Ver producto