Myosin VIIB (MYO7B) Antibody
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935106861
info@markelab.com
Precio
364€ (100 µg)
Antibody anti-MYO7B
proveedor
Abbexareference
abx235508Tested Applications
ELISA, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
MYO7B Antibody is a Rabbit Polyclonal against MYO7B.
Background
Myosin VIIB (MYO7B) is a motor protein from the myosin family, which is involved in ATP-dependent cellular movements Myosin VIIB, like other myosins, moves along actin filaments, converting chemical energy into mechanical work This motor protein is crucial for cellular processes such as vesicular transport, endocytosis, and cell migration MYO7B plays a specific role in the auditory and visual systems, where it is involved in the function of sensory cells, including the hair cells of the inner ear and photoreceptors in the retina In the inner ear, MYO7B helps maintain the structure and function of hair cells, which are responsible for detecting sound vibrations and balancing signals Disruption in MYO7B function leads to hearing loss and progressive blindness, as seen in Usher syndrome type 2, where both deafness and vision impairment occur due to defects in inner ear and retinal cells
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Myosin VIIB (MYO7B)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IHC
purity
≥ 95% (SDS-PAGE)
purification
Purified by immunogen affinity chromatography.
recommended dilution
IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
size 1
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
MYO7B
dry ice
No
availability
Shipped within 5-12 working days.
alias
Unconventional myosin-VIIb
uniprot id
note
Concentration: 2 mg/ml - Validity: 12 months.
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