Myosin VIIB (MYO7B) Antibody
377€ (100 µg)
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Name
Myosin VIIB (MYO7B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx235508
Tested Applications
ELISA, IHC
Description
MYO7B Antibody is a Rabbit Polyclonal against MYO7B.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Myosin VIIB (MYO7B) Immunogen: myosin VIIB |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6PIF6 |
| Gene ID | 4648 |
| OMIM | 606541 |
| Alias | Unconventional myosin-VIIb |
| Background | Antibody anti-MYO7B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Myosin VIIB (MYO7B) is a motor protein from the myosin family, which is involved in ATP-dependent cellular movements Myosin VIIB, like other myosins, moves along actin filaments, converting chemical energy into mechanical work This motor protein is crucial for cellular processes such as vesicular transport, endocytosis, and cell migration MYO7B plays a specific role in the auditory and visual systems, where it is involved in the function of sensory cells, including the hair cells of the inner ear and photoreceptors in the retina In the inner ear, MYO7B helps maintain the structure and function of hair cells, which are responsible for detecting sound vibrations and balancing signals Disruption in MYO7B function leads to hearing loss and progressive blindness, as seen in Usher syndrome type 2, where both deafness and vision impairment occur due to defects in inner ear and retinal cells
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