Myosin VIIA (MYO7A) Antibody (HRP)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
MYO7A Antibody (HRP) is a Rabbit Polyclonal against MYO7A conjugated to HRP.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Myosin VIIA (MYO7A) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | HRP |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q13402 |
Gene ID | 4647 |
NCBI Accession | NP_000251.3 |
OMIM | 276900 |
Alias | DFNB2,MYU7A,NSRD2,USH1B,DFNA11,MYOVIIA,Unconventional myosin-VIIa |
Background | Antibody anti-MYO7A |
Status | RUO |
Descripción
Myosin VIIA (MYO7A) is a motor protein that belongs to the myosin family, which converts chemical energy from ATP hydrolysis into mechanical work, enabling cellular movement MYO7A is essential for cellular processes such as vesicular trafficking, cell adhesion, and the transport of organelles It is particularly important in the sensory cells of the inner ear, where it plays a critical role in the function of hair cells responsible for hearing and balance MYO7A’s function is also crucial in the retina, where it helps transport proteins and other cellular components to the outer segments of photoreceptor cells Defects in MYO7A are associated with Usher syndrome type 1, a genetic disorder that causes congenital deafness and progressive blindness due to defects in the inner ear and retina MYO7A also plays a role in maintaining the structure of the photoreceptors and inner ear cells, making it an important protein for both sensory function and cellular transport in specialized cells of the sensory organs
Related Products

MYO7A antibody
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial(RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity(By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Ver Producto
Myosin VIIA (MYO7A) Antibody
Myosin Viia Polyclonal Antibody is a Rabbit Polyclonal antibody against Myosin Viia Polyclonal Antibody.
Ver Producto