Myosin VIIA (MYO7A) Antibody
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Description
MYO7A Antibody is a Rabbit Polyclonal against MYO7A.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Myosin VIIA (MYO7A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13402 |
| Gene ID | 4647 |
| NCBI Accession | NP_000251.3 |
| OMIM | 276900 |
| Alias | DFNB2,MYU7A,NSRD2,USH1B,DFNA11,MYOVIIA,Unconventional myosin-VIIa |
| Background | Antibody anti-MYO7A |
| Status | RUO |
| Note | Concentration: 3.5 mg/ml - |
Descripción
Myosin VIIA (MYO7A) is a motor protein that belongs to the myosin family, which converts chemical energy from ATP hydrolysis into mechanical work, enabling cellular movement MYO7A is essential for cellular processes such as vesicular trafficking, cell adhesion, and the transport of organelles It is particularly important in the sensory cells of the inner ear, where it plays a critical role in the function of hair cells responsible for hearing and balance MYO7A’s function is also crucial in the retina, where it helps transport proteins and other cellular components to the outer segments of photoreceptor cells Defects in MYO7A are associated with Usher syndrome type 1, a genetic disorder that causes congenital deafness and progressive blindness due to defects in the inner ear and retina MYO7A also plays a role in maintaining the structure of the photoreceptors and inner ear cells, making it an important protein for both sensory function and cellular transport in specialized cells of the sensory organs
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