Myosin IXB (MYO9B) Antibody
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Description
Myosin Ixb Antibody is a Rabbit Polyclonal antibody against Myosin Ixb.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Myosin IXB (MYO9B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13459 |
| Gene ID | 4650 |
| NCBI Accession | NP_004136.2, NM_004145.3 |
| OMIM | 602129 |
| Background | Antibody anti-MYO9B |
| Status | RUO |
Descripción
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MYO9B antibody
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions(PubMed:9490638). Also acts as a GTPase activator for RHOA(PubMed:9490638, PubMed:26529257). Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. This is regulated by its interaction with the SLIT2 receptor ROBO1; interaction with ROBO1 impairs interaction with RHOA and subsequent activation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA(PubMed:26529257).
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Myosin IXB (MYO9B) Antibody
Rabbit polyclonal antibody against MYO9B protein. Immunogen region is N-terminal.
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Myosin IXB (MYO9B) Antibody
Myosin Ixb Antibody is a Rabbit Polyclonal antibody against Myosin Ixb.
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