Myosin IA (MYO1A) Antibody

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Description
Myosin IA (MYO1A) Antibody is a Rabbit Polyclonal antibody against Myosin IA (MYO1A).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Myosin IA (MYO1A) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by affinity chromatography using epitope-specific immunogen. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9UBC5 |
Gene ID | 4640 |
Background | Antibody anti-MYO1A |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Myosin IA (MYO1A) Antibody
MYO1A belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein envelops an actin core bundle that, by comparison, is static in structure.
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Human Myosin IA (MYO1A) Protein
Recombinant Myosin IA (MYO1A) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
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