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Myeloid Cell Surface Antigen CD33 (CD33) Antibody
proveedor
Abbexareference
abx027453Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Myeloid Cell Surface Antigen CD33 (CD33)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified through a protein A column, followed by peptide affinity purification.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CD33
dry ice
No
availability
Shipped within 5-10 working days.
alias
p67,SIGLEC3,SIGLEC-3,CD33rSiglec,Sialic acid-binding Ig-like lectin 3,Myeloid cell surface antigen CD33
uniprot id
note
This product is for research use only.
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