Myeloid Cell Surface Antigen CD33 (CD33) Antibody
299€ (0.1 mg)
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935106861
info@markelab.com
name
Myeloid Cell Surface Antigen CD33 (CD33) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx139238
tested applications
WB, IHC, IF/ICC, FCM, IP, FUNC
Description
CD33 Antibody is a Mouse Monoclonal against CD33.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Myeloid Cell Surface Antigen CD33 (CD33) |
| Host | Mouse |
| Reactivity | Human, Monkey |
| Recommended Dilution | Validated in IHC-F and ICC. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | R796 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | WB, IHC, IF/ICC, FCM, IP, FUNC |
| Buffer | LE/AF PBS solution, 0.2 µm filter sterilized. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P20138 |
| Gene ID | 945 |
| Alias | p67,SIGLEC3,SIGLEC-3,CD33rSiglec,Sialic acid-binding Ig-like lectin 3,Myeloid cell surface antigen CD33 |
| Background | Antibody anti-CD33 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
CD33, also known as Siglec-3 (Sialic acid-binding Ig-like lectin 3), is a transmembrane receptor expressed primarily on cells of myeloid lineage. It belongs to the immunoglobulin (Ig) superfamily and plays a significant role in the regulation of innate immunity. CD33 was first identified in the late 1980s as a marker on acute myeloid leukemia (AML) cells, making it a focal point for research in hematological malignancies. This glycoprotein is encoded by the CD33 gene located on chromosome 19q13.3. CD33 is involved in cellular signaling processes that modulate immune cell function and survival.
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