MYC (pT58) Antibody

Descripción

MYC participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

MYC (pT58)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, DB

purification

Purified by protein A affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with peptides. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

MYC

dry ice

availability

Shipped within 5-10 working days.

alias

MRTL,MYCC,c-Myc,bHLHe39,Transcription factor p64,Proto-oncogene c-Myc,Class E basic helix-loop-helix protein 39

uniprot id

https://www.uniprot.org/uniprotkb/P01106

NCBI accession

NP_002458.2

note

This product is for research use only.

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