Myc (pS62) DNA-Binding ELISA Kit

Product Graph
585€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Myc (pS62) DNA-Binding ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx596625
tested applications
ELISA

Description

Myc (pS62) DNA Binding ELISA Kit is an ELISA Kit against Myc (pS62).

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Myc (pS62)
Reactivity
Human, Mouse
Detection Method
Colorimetric
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Tested Applications
ELISA
Availability
Shipped within 1-2 weeks.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P01106
Gene ID
9531
OMIM
113970
Alias
MRTL,MYCC,c-Myc,bHLHe39,Transcription factor p64,Proto-oncogene c-Myc,Class E basic helix-loop-helix protein 39
Background
Elisa Kits for: Myc
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

The MYC proto-oncogene encodes a basic helix-loop-helix (bHLH) transcription factor that is central to regulating cell growth, proliferation, and metabolism. It acts as a master regulator by binding to E-box sequences within the genome to control the transcription of numerous genes involved in key cellular processes, such as ribosome biogenesis, cell cycle progression, and apoptosis. Dysregulation of MYC, often through overexpression or amplification, is a hallmark of many cancers, including Burkitt lymphoma and various solid tumors. This dysregulation promotes uncontrolled cell proliferation and impairs apoptosis, contributing to tumorigenesis. Additionally, MYC interacts with multiple co-factors and chromatin-modifying complexes, further amplifying its impact on the epigenetic landscape. Given its critical role in oncogenesis, MYC is extensively studied as a therapeutic target, with ongoing efforts to develop strategies to inhibit its activity or downstream pathways to treat MYC-driven malignancies. Its widespread effects on cellular physiology underscore its importance in both normal development and disease.
Related Products
abx596625
Myc (pS62) DNA-Binding ELISA Kit
Myc (pS62) DNA Binding ELISA Kit is an ELISA Kit against Myc (pS62).
Ver Producto
abx596626
Myc (pT58) DNA-Binding ELISA Kit
Myc (pT58) DNA Binding ELISA Kit is an ELISA Kit against Myc (pT58).
Ver Producto