Myc Proto-Oncogene Protein (MYC) Antibody is a Rabbit Polyclonal antibody for the detection of c-MYC. MYC contains one basic helix-loop-helix (bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186]
Primary Antibodies
Polyclonal
Human, Mouse, Rat
Myc Proto-Oncogene Protein (MYC)
Rabbit
Unconjugated
Liquid
ELISA, WB
≥ 95% (SDS-PAGE)
Purified by immunogen affinity chromatography.
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
100 µg
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
MYC
No
Shipped within 5-12 working days.
This product is for research use only.
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