DNA Mismatch Repair Protein Mlh1 (MLH1) Antibody
383.5€ (100 µl)
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Name
DNA Mismatch Repair Protein Mlh1 (MLH1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx012221
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: DNA Mismatch Repair Protein Mlh1 (MLH1) Immunogen: Purified recombinant fragment of MLH1 (aa381-483) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human, Monkey |
| Assay Type | Concentration: Not determined. |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | 85 kDa |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P40692 |
| Gene ID | 4292 |
| NCBI Accession | NP_000240.1, NM_000249.3 |
| OMIM | 114500 |
| Background | Antibody anti-MLH1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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