Multidrug Resistance-Associated Protein 4 (ABCC4) Antibody

Este producto es parte de ABCC - ATP binding cassette subfamily C
Multidrug Resistance-Associated Protein 4 (ABCC4) Antibody

Pida mas información

935106861

info@markelab.com

Precio

162.5€ (20 µg)

Antibody anti-ABCC4

proveedor

Abbexa

reference

abx301046

Tested Applications

ELISA, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

ABCC4 Antibody is a Rabbit Polyclonal against ABCC4.


Background

ABCC4, also known as multidrug resistance-associated protein 4 (MRP4), is an ATP-binding cassette transporter expressed in various tissues, including the liver, kidneys, and endothelial cells of the blood-brain barrier. It exports a wide range of substrates, including cyclic nucleotides, prostaglandins, antiviral drugs, and chemotherapeutic agents, from cells. ABCC4’s activity plays a critical role in cellular signaling by regulating intracellular levels of cyclic AMP and GMP. It is also involved in drug resistance, where its overexpression limits the intracellular accumulation of therapeutic agents. ABCC4 is upregulated in response to oxidative stress and inflammation, highlighting its role in protecting cells from toxic insults. Its diverse substrate specificity and involvement in drug efflux make ABCC4 a significant target in pharmacological research and disease management.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Multidrug Resistance-Associated Protein 4 (ABCC4)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, IF/ICC


purity

> 95%


purification

Purified by Protein G.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

ABCC4


dry ice

No


availability

Shipped within 5-10 working days.


alias

MOAT-B,MOATB,MRP4,Multidrug resistance-associated protein 4


NCBI accession

NP_001098985.1, NM_001105515.2, NP_001288758.1, NM_001301829.1, NP_001288759.1, NM_001301830.1, NP_005836.2, NM_005845.4


note

This product is for research use only.


Quizá le pueda interesar

Human ABCC4(Multidrug resistance-associated protein 4) ELISA Kit

Human ABCC4(Multidrug resistance-associated protein 4) ELISA Kit

proveedor

FineTest

reference

EH1167

reactivity

human

status

RUO

Precio a consultar

Ver más

Multidrug Resistance-Associated Protein 4 (ABCC4) Antibody

Multidrug Resistance-Associated Protein 4 (ABCC4) Antibody

proveedor

Abbexa

reference

abx001810

Tested Applications

WB, IHC, IF/ICC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

ABCC4 Antibody is a Rabbit Polyclonal antibody against ABCC4. The protein encoded by this gene is a member of the superf...

175€ (20 µl)

Ver más

Multidrug Resistance-Associated Protein 4 (ABCC4) Antibody

Multidrug Resistance-Associated Protein 4 (ABCC4) Antibody

proveedor

Abbexa

reference

abx015754

Tested Applications

ELISA, IHC, FCM

reactivity

Human

status

RUO

clonality

Monoclonal

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins ...

362.5€ (100 µl)

Ver más