MADCAM1 antibody

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935106861
info@markelab.com
name
MADCAM1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04927
tested applications
ELISA, IHC

Description

Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
mucosal vascular addressin cell adhesion molecule 1 (MADCAM1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
40 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q13477
Gene ID
8174
Alias
Mucosal addressin cell adhesion molecule 1 (MAdCAM-1, hMAdCAM-1),MADCAM1
Background
Antibody anti-MADCAM1
Status
RUO
Note
Mol. Weight 40 kDa

Descripción

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FNab04927

MADCAM1 antibody

Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Ver Producto