MADCAM1 antibody

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935106861
info@markelab.com
name
MADCAM1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04927
tested applications
ELISA, IHC
Description
Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | mucosal vascular addressin cell adhesion molecule 1 (MADCAM1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 40 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q13477 |
Gene ID | 8174 |
Alias | Mucosal addressin cell adhesion molecule 1 (MAdCAM-1, hMAdCAM-1),MADCAM1 |
Background | Antibody anti-MADCAM1 |
Status | RUO |
Note | Mol. Weight 40 kDa |
Descripción
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MADCAM1 antibody
Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Ver Producto