mRNA-Decapping Enzyme 1A (DCP1A) Antibody

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Description
DCP1A Antibody is a Rabbit Polyclonal Antibody against DCP1A.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mRNA-Decapping Enzyme 1A (DCP1A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NPI6 |
| Gene ID | 55802 |
| NCBI Accession | NP_060873.4 |
| Background | Antibody anti-DCP1A |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
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