Mouse WD repeat and FYVE domain-containing protein 2 (WDFY2) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Mouse WD repeat and FYVE domain-containing protein 2 (WDFY2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx553352
tested applications
ELISA
Description
Mouse WD repeat and FYVE domain-containing protein 2 (WDFY2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse WD repeat and FYVE domain-containing protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | WD repeat and FYVE domain-containing protein 2 (WDFY2) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q8BUB4 |
Gene ID | 268752 |
Alias | PROF,WDF2,ZFYVE22,Propeller-FYVE protein,WD40- and FYVE domain-containing protein 2 |
Background | Elisa kits for WDFY2 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
WD repeat and FYVE domain containing 2 (WDFY2) shares similarities with WDFY1, as it also contains WD repeats and a FYVE domain that enable it to participate in cellular signaling and membrane trafficking. This protein is involved in processes like receptor endocytosis and lysosomal degradation, where it interacts with other proteins to regulate the movement of vesicles within the cell. Like WDFY1, WDFY2 binds phosphoinositides, which are key molecules in cellular membrane dynamics. The role of WDFY2 in vesicular sorting makes it crucial for the regulation of the recycling of various membrane receptors, thus ensuring proper cell signaling and receptor function. WDFY2 also plays a role in immune responses, influencing processes like antigen presentation and immune cell activation. Studies suggest that WDFY2's function is essential for maintaining immune homeostasis, and its dysregulation has been linked to autoimmune disorders and immune deficiencies. As a result, understanding how WDFY2 interacts with other cellular machinery is important for developing therapeutic strategies targeting vesicular trafficking in diseases related to immune dysfunction.
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