Mouse UBX domain-containing protein 6 (UBXN6) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse UBX domain-containing protein 6 (UBXN6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx552435
tested applications
ELISA
Description
Mouse UBX domain-containing protein 6 (UBXN6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse UBX domain-containing protein 6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | UBX domain-containing protein 6 (UBXN6) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q99PL6 |
| Gene ID | 66530 |
| Alias | UBXD1,UBXDC2,UBX domain-containing protein 1 |
| Background | Elisa kits for UBXN6 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
UBX domain protein 6 (UBXN6) is a p97/VCP-interacting protein that functions as a key regulator of protein homeostasis by participating in proteasome and autophagy pathways UBXN6 facilitates the extraction and degradation of ubiquitinated misfolded proteins during endoplasmic reticulum-associated degradation (ERAD), playing a vital role in cellular quality control processes It also modulates autophagy by linking p97 to lysosomal pathways for the clearance of protein aggregates Studies show that UBXN6 is involved in cellular stress responses, particularly under proteotoxic conditions where protein turnover mechanisms are critical Dysregulation of UBXN6 leads to protein aggregation and cellular dysfunction, contributing to neurodegenerative diseases such as Parkinson’s and Huntington’s diseases UBXN6 also plays a role in cancer, where its regulation of proteostasis supports tumor cell survival under stress conditions and influences apoptosis Its role in maintaining cellular integrity and proteasome activity highlights its importance in protein quality control and stress adaptation
Related Products
UBXN6 antibody
Ver Producto
UBX Domain-Containing Protein 6 (UBXN6) Antibody
UBXN6 acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. UBXN6 is MDM2 stabilization leads to MDM2-dependent TP53 degradation.
Ver Producto
UBX Domain-Containing Protein 6 (UBXN6) Antibody
Ubx Domain Protein 6 Antibody is a Rabbit Polyclonal antibody against Ubx Domain Protein 6.
Ver Producto