Mouse UBX domain-containing protein 10 (UBXN10) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Mouse UBX domain-containing protein 10 (UBXN10) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx552415
tested applications
ELISA
Description
Mouse UBX Domain-Containing Protein 10 (UBXN10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse UBX Domain-Containing Protein 10 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | UBX Domain-Containing Protein 10 (UBXN10) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q8BG34 |
Gene ID | 212190 |
Alias | UBXD3,UBX domain-containing protein 3 |
Background | Elisa kits for UBXN10 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
UBX domain protein 10 (UBXN10) is a member of the UBX domain-containing protein family, which interacts with p97/VCP to regulate protein degradation and cellular quality control processes UBXN10 acts as a cofactor for p97, facilitating the extraction and turnover of ubiquitinated proteins during ER-associated degradation (ERAD) and other proteasome-dependent pathways It plays a critical role in maintaining protein homeostasis and stress responses in the endoplasmic reticulum Dysregulation of UBXN10 expression has been linked to cellular stress and apoptotic pathways, where it influences p97’s activity and protein clearance Emerging studies suggest a role for UBXN10 in cellular differentiation, particularly in tissues with high protein synthesis demands, such as skeletal muscle and the immune system UBXN10 is also implicated in cancer progression, where altered protein degradation pathways support tumor survival and resistance to therapy Its function in regulating proteostasis highlights its importance in maintaining cellular quality control and response to proteotoxic stress
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