Mouse Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
546€ (96 tests)
Elisa kits for TNFRSF1A
proveedor
Abbexareference
abx254621Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A) concentrations in serum, plasma and other biological fluids.
Background
TNFRSF1A , also known as Tumor Necrosis Factor Receptor Superfamily Member 1A or TNFR1 , is a prominent cell surface receptor that binds tumor necrosis factor-alpha (TNF-α). TNFR1 plays a critical role in regulating immune responses, cell survival, apoptosis, and inflammation, making it an essential component in both innate and adaptive immunity. The TNFRSF1A gene is located on chromosome 12p13.31 and encodes a protein that is expressed in nearly all cell types, with high expression in immune cells, epithelial cells, and neurons. As a member of the TNF receptor superfamily, TNFRSF1A is involved in multiple signaling pathways, depending on cellular and environmental conditions. Upon binding to TNF-α, TNFR1 can trigger both pro-inflammatory responses and cell death pathways, depending on the context of signaling and additional molecules present. This receptor’s dual role is tightly regulated, as overactivation of TNFR1-mediated pathways can lead to pathological inflammation, while insufficient TNFR1 activity may hinder immune responses.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Receptor Superfamily Member 1A / CD120a (TNFRSF1A)
reactivity
Mouse
test range
7.81 pg/ml - 500 pg/ml
sensitivity
4.69 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
FPF,p55,p60,TBP1,TNF-R,TNFAR,TNFR1,p55-R,CD120a,TNFR55,TNFR60,TNF-R-I,TNF-R55,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TNFRSF1A
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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