Mouse Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) ELISA Kit

Este producto es parte de TNFRSF10B - TNF receptor superfamily member 10b
Mouse Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for TNFRSF10B

proveedor

Abbexa

reference

abx520893

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

TNFRSF10B (TNF receptor superfamily member 10b), also known as TRAIL-R2, DR5 (death receptor 5), or KILLER (Killer/DR5), is a cell surface receptor in the TNF receptor superfamily. It plays a crucial role in mediating apoptosis, especially in transformed or cancerous cells, through interaction with the TNF-related apoptosis-inducing ligand (TRAIL). Like other members of the death receptor family, TNFRSF10B is part of the body's natural mechanism for controlling cell growth, immune responses, and tumor suppression. TRAIL selectively targets cells exhibiting TNFRSF10B expression, making it a key pathway in immune surveillance and tumor inhibition, while leaving normal cells relatively unaffected. Due to its selective induction of apoptosis in abnormal cells, TNFRSF10B has become an important target in cancer therapeutics.

Características del producto

category

ELISA Kits


immunogen target

Tumor Necrosis Factor Receptor Superfamily Member 10B / DR5 (TNFRSF10B)


reactivity

Mouse


test range

0.78 ng/ml - 50 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

DR5,CD262,KILLER,TRICK2,TRICKB,ZTNFR9,TRAILR2,TRICK2A,TRICK2B,TRAIL-R2,KILLER/DR5,Death receptor 5,TNF-related apoptosis-inducing ligand receptor 2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TNFRSF10B


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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