Mouse Transient Receptor Potential Cation Channel Subfamily M Member 8 (TRPM8) ELISA Kit

Product Graph
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Transient Receptor Potential Cation Channel Subfamily M Member 8 (TRPM8) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx551437
tested applications
ELISA

Description

Mouse Transient Receptor Potential Cation Channel Subfamily M Member 8 (TRPM8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transient Receptor Potential Cation Channel Subfamily M Member 8 (TRPM8) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Transient Receptor Potential Cation Channel Subfamily M Member 8 (TRPM8)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.08 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8R4D5
Background
Elisa kits for TRPM8
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Related Products

EH13240

Human TRPM8 (Transient receptor potential cation channel subfamily M member 8) ELISA Kit

Ver Producto
FNab09023

TRPM8 antibody

Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonist menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing. In prostate cancer cells, shows strong inward rectification and high calcium selectivity in contrast to its behavior in normal cells which is characterized by outward rectification and poor cationic selectivity. Plays a role in prostate cancer cell migration(PubMed:25559186). Isoform 2 and isoform 3 negatively regulate menthol-and cold-induced channel activity by stabilizing the closed state of the channel.

Ver Producto
abx006769

Transient Receptor Potential Cation Channel Subfamily M Member 8 (TRPM8) Antibody

TRPM8 Antibody is a Rabbit Polyclonal Antibody against TRPM8.

Ver Producto