Mouse Toll Like Receptor 2 (TLR2) Protein
1079€ (100 µg)
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935106861
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name
Mouse Toll Like Receptor 2 (TLR2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692566
tested applications
SDS-PAGE
Description
Mouse TLR2 Protein is a recombinant protein from Mouse produced in Baculovirus-Insect Cells. A DNA sequence encoding the mouse TLR2 (Q9QUN7) (Met1-Gln587) was fused with a polyhistidine tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | TLR2 |
| Host | Insect |
| Origin | Mouse |
| Observed MW | Molecular Weight: 64.8 kDa Sequence Fragment: Met1-Gln587 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9QUN7 |
| Alias | Toll-like receptor 2,TIL4,CD282,Toll/interleukin-1 receptor-like protein 4 |
| Background | Protein TLR2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Toll-like receptor 2 (TLR2) is an essential component of the innate immune system, known for its role in recognizing and responding to pathogen-associated molecular patterns (PAMPs). TLR2 is part of the toll-like receptor (TLR) family, which detects structural components specific to pathogens and activates immune responses. TLR2 is particularly versatile, recognizing a broad array of ligands from bacteria, fungi, and viruses, and functions primarily by forming heterodimers with other TLRs, specifically TLR1 and TLR6. These heterodimers expand TLR2’s range of ligand recognition, including lipoproteins, lipopeptides, peptidoglycan, and lipoteichoic acid, enabling it to respond effectively to both Gram-positive and Gram-negative bacteria. The expression of TLR2 is predominantly found in immune cells such as macrophages, dendritic cells, and monocytes. TLR2’s activity is integral to the initiation of pro-inflammatory responses that support early immune defense. As such, it plays a pivotal role in the development of both innate and adaptive immunity by bridging the two responses through cytokine release and antigen presentation. Due to its broad functionality and critical role in immunity, TLR2 has become a focus for research into infections, inflammation, and immune-related diseases, as well as a potential target for immunotherapy.
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