Mouse Thromboxane A2 receptor (TBXA2R) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TBXA2R
proveedor
Abbexareference
abx548560Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Thromboxane A2 receptor (TBXA2R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Thromboxane A2 receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
The thromboxane A2 receptor (TBXA2R), also known as TP, is a G protein-coupled receptor activated by thromboxane A2 (TXA2), a lipid mediator that promotes vasoconstriction, platelet aggregation, and inflammation. TBXA2R primarily couples to Gq and G12/13 proteins, activating phospholipase C (PLC), increasing intracellular calcium levels, and triggering Rho-mediated pathways that regulate smooth muscle contraction and platelet activation. TBXA2R is highly expressed in platelets, vascular smooth muscle cells, and immune cells, where it plays a pivotal role in hemostasis, thrombosis, and vascular tone. Dysregulation of TBXA2R signaling contributes to thrombotic disorders, hypertension, and atherosclerosis. TBXA2R antagonists, such as terutroban, are being developed as antithrombotic agents to reduce platelet aggregation and treat cardiovascular diseases. Targeting TBXA2R provides therapeutic potential for managing thrombosis, pulmonary hypertension, and inflammatory vascular diseases by modulating TXA2-mediated effects.
Características del producto
category
ELISA Kits
immunogen target
Thromboxane A2 receptor (TBXA2R)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
TBXA2R,prostanoid TP receptor,TXA2-R,BDPLT13
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TBXA2R
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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