Mouse T-Cell-Specific Surface Glycoprotein CD28 (CD28) Protein
234€ (10 µg)
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935106861
info@markelab.com
name
Mouse T-Cell-Specific Surface Glycoprotein CD28 (CD28) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168377
tested applications
WB, SDS-PAGE
Description
Mouse Cluster Of Differentiation 28 (CD28) Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | T-Cell-Specific Surface Glycoprotein CD28 (CD28) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 18.7 kDa Observed MW (SDS-PAGE): 19 kDa Concentration: Prior to lyophilization: 150 µg/ml Sequence Fragment: Asn20-Leu150 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P31041 |
| Alias | Tp44,T-cell-specific surface glycoprotein CD28 |
| Background | Protein CD28 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD28 is a pivotal co-stimulatory molecule expressed on the surface of T cells. It plays a crucial role in the activation and survival of T cells, which are essential components of the adaptive immune system. CD28 is predominantly found on CD4+ T helper cells, although it is also present on a subset of CD8+ cytotoxic T cells. The interaction of CD28 with its ligands, CD80 (B7-1) and CD86 (B7-2), on antigen-presenting cells (APCs) provides the necessary secondary signals that, together with signals from the T cell receptor (TCR), lead to full T cell activation, proliferation, and differentiation. The presence and function of CD28 are vital for initiating effective immune responses and for maintaining T cell homeostasis and tolerance.
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