Mouse Suppressor of Cytokine Signaling 6 (SOCS6) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
643.5€ (96 tests)
Elisa kits for SOCS6
proveedor
Abbexareference
abx546666Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Suppressor of Cytokine Signaling 6 (SOCS6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Suppressor of Cytokine Signaling 6 (SOCS6) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Background
SOCS6 is a member of the SOCS protein family that regulates cytokine and growth factor signaling pathways, particularly those mediated by insulin and receptor tyrosine kinases (RTKs). It inhibits signaling by targeting receptor complexes and signaling intermediates for ubiquitin-mediated degradation via its SOCS box domain, thus fine-tuning pathways such as the PI3K/Akt and MAPK cascades. SOCS6 is broadly expressed in tissues like the liver, pancreas, and skeletal muscle, where it regulates processes like cell growth, glucose metabolism, and insulin sensitivity. It has a role in tumor suppression by inhibiting growth factor signaling and promoting apoptosis in cancer cells. Dysregulation of SOCS6 is linked to metabolic disorders, including insulin resistance and diabetes, as well as cancer progression due to impaired signaling control. Knockdown studies reveal enhanced RTK activity, increased cellular proliferation, and reduced apoptosis, highlighting its role as a regulator of metabolic signaling, growth, and tumor suppression.
Características del producto
category
ELISA Kits
immunogen target
Suppressor of Cytokine Signaling 6 (SOCS6)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
size 1
96 tests
alias
SOSC6,CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
SOCS6
dry ice
No
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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