Mouse Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit

Este producto es parte de CD14 - Cluster of Differentiation 14
Mouse Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit
585€ (96 tests)

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Name
Mouse Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx353219
Tested Applications
ELISA

Description

Mouse Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Soluble Cluster of Differentiation 14 (sCD14) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Soluble Cluster of Differentiation 14 (sCD14)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
1.56 ng/ml - 100 ng/ml
Sensitivity
0.94 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P10810
Alias
Cluster Of Differentiation 14,CD14,Myeloid Cell-Specific Leucine-Rich Glycoprotein,Monocyte differentiation antigen CD14
Background
Elisa Kits for: CD14
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Soluble Cluster of Differentiation 14 (sCD14) is a crucial glycoprotein primarily expressed on the surface of monocytes, macrophages, and neutrophils, as well as existing in a soluble form (sCD14) in circulation. This molecule acts as a co-receptor for the detection of bacterial lipopolysaccharides (LPS), a component of Gram-negative bacterial cell walls, in conjunction with Toll-like receptor 4 (TLR4) and MD-2. CD14 is pivotal in innate immunity, where it aids in the recognition of pathogens and triggers immune responses. Soluble CD14 is particularly significant in tissues and cells lacking membrane-bound CD14, enabling a broader immune response. Dysregulation of CD14 levels is linked to various inflammatory and infectious diseases, including sepsis, atherosclerosis, and autoimmune conditions. As a biomarker, soluble CD14 is used in research and clinical diagnostics to assess inflammation and immune activation. It plays an essential role in understanding host-pathogen interactions and inflammatory pathways.

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